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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1914633Generated: October 31, 2026

Chloride → HCID 178426315, compound

https://huagongshe.com/reaction/1914633

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantPyrazoleHCID 1048—
ReactantBenzamideHCID 2331—
ReactantHCID 178501210HCID 178501210—
ReactantHCID 178520978HCID 178520978—
ProductHCID 178426315HCID 178426315—

Reaction Steps

The compounds of the following tabulated Examples (Table 1) are prepared by a similar method to that of Example 1 using the appropriate benzamide or pyrazole starting materials (prepared analogously to trans-2-chloro-N-(4-formyl-cyclohexyl)-5-trifluoromethyl-benzamide from trans-4-amino-cyclohexylcarboxylic acid methyl ester hydrochloride and the appropriate benzoly chloride) and the appropriate amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08614213B2
Source datasetuspto-grants-2013_12
ORD IDord-f589020e193d4bbb87ce3f946935ce29
Source noteuspto-grants-2013_12