HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium formate → (4-Amino-3-methyl-cyclohexylmethyl)-phenyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium formate | HCID 2723923 | — |
| Reactant | HCID 67185307 | HCID 67185307 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (4-Amino-3-methyl-cyclohexylmethyl)-phenyl-amine | HCID 67185375 | — |
Reaction Steps
(4-Benzylamino-3-methyl-cyclohexylmethyl)-phenyl-amine (160 mg, 0.52 mmol) and ammonium formate (164 mg, 2.60 mmol) in EtOH (5 mL) is treated with 10% Pd/C (30 mg) and heated at reflux for 2 hours. The Pd/C is removed by filtration and washed with MeOH. The filtrate is concentrated in vacuo to afford the title compound which is used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08614213B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-4680f0def9b64cd982a3d20f255e5b33 |
| Source note | uspto-grants-2013_12 |