反应详情

Ethyl 8-iodo-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate (384 mg, 1 mmol) was suspended in anhydrous ethanol (10 mL) and treated with a 1.5 M solution of potassium hydroxide in ethanol (6.6 mL, 10 mmol) at room temperature, overnight. The resulting precipitate was collected by filtration to give the title compound (323 mg, 82% yield) as a white solid.

1. filtrationThe resulting precipitate was collected by filtration