Nitric Acid → HCID 49820462, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of (6,7-dibromo-5-hydroxybenzofuran-3-yl)(4-(thiazol-2-ylmethoxy)phenyl)methanone (70 mg, 0.137 mmol) in acetic acid (1 mL) was added nitric acid—69% (44.2 μl, 0.687 mmol) and the mixture heated at 60° C. for 1 hour. During this time the suspension turned bright red/orange and partially dissolved. After this time, the mixture was added to ice-water, then filtered to afford crude product as a red solid.

Provenance & Evidence