Sodium Hydroxide → HCID 13713019, compound

HRID 1914807Notes

Reaction equation

HRID 1914807 reaction equation
[CH3:1][NH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH2:9].[CH3:10][NH:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=O)=[CH:14][CH:13]=1.[OH-].[Na+]>O>[CH3:10][NH:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]2[N:2]([CH3:1])[C:3]3[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=3[N:9]=2)=[CH:14][CH:13]=1

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 663454-(Methylamino)benzoic acidHCID 78498N-Methyl-o-phenylenediamine

Product 1

HCID 13713019HCID 13713019, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

10.14 mL (86.5 mmol) N-Methyl-o-phenylenediamine and 13.08 g (86.5 mmol) 4-(methylamino)benzoic acid are stirred in 70.0 g polyphosphoric acid at 200° C. for 3 hours. The mixture is cooled to 80° C., poured into water and stirred over night at RT. The mixture is alkalinized with sodium hydroxide solution. The precipitate is filtered off and washed with water. The product is dried in vacuo at 50° C.

Workup

  1. filtrationThe precipitate is filtered off
  2. washwashed with water
  3. customThe product is dried in vacuo at 50° C.

Sources & evidence

ORD record
ord-d648c7093ffc4159ad96d844d97e66a5
Source dataset
uspto-grants-2013_12
Patent number
US08614238B2

Reaction notes

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