HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Nitrophenyl)imidazo(1,2-a)pyridine → 4-(Imidazo(1,2-a)pyridin-2-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Nitrophenyl)imidazo(1,2-a)pyridine | HCID 201134 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(Imidazo(1,2-a)pyridin-2-yl)aniline | HCID 696936 | — |
Reaction Steps
4.50 g (18.8 mmol) 2-(4-Nitro-phenyl)-imidazo[1,2-a]pyridine and 0.45 g Raney-Nickel are stirred at RT under hydrogen (50 psi) in 50 mL ethanol and 50 mL ethyl acetate. The mixture is filtered and the solvent is evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08614238B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-05eb21efd5b940019ffc25c7d8f64c74 |
| Source note | uspto-grants-2013_12 |