Hydrochloric Acid → HCID 86762192, compound

Participants

Reaction Steps

Intermediate I-6a was prepared from (4-bromo-2-fluoro-phenyl)-(2,3-difluoro-5-methoxy-6-nitro-phenyl)-amine (I-4a: 16 g, 0.0425 mol), zinc powder (19.6 g, 0.298 mmol) and concentrated HCl (45 mL) using procedures analogous the preparation of Intermediate (I-5a) above to afford the product (85% yield). H1NMR (CDCl3, 300 MHz): δ 7.24 (dd, 1H), 7.06 (dt, 1H), 6.66-6.58 (m, 1H), 6.36 (t, 1H), 5.36 (s, 1H), 3.82 (s, 3H).

Provenance & Evidence