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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 191510Generated: October 25, 2026

Acetate → 5-{2-[2-Chloro-4-(4-fluoro-3-methoxy-phenoxy)-phenyl]-1-hydroxy-1-trifluoromethyl-propyl}-1-methyl-1H-pyridin-2-one

https://huagongshe.com/reaction/191510

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetateHCID 175—
ReactantPyridineHCID 1049—
ReactantDichloromethaneHCID 6344—
ReactantCupric cationHCID 27099—
Reactant(4-Fluoro-3-methoxyphenyl)boronic acidHCID 44558185—
Reactant5-[2-(2-Chloro-4-hydroxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1-methyl-1H-pyridin-2-oneHCID 57421314—
Product5-{2-[2-Chloro-4-(4-fluoro-3-methoxy-phenoxy)-phenyl]-1-hydroxy-1-trifluoromethyl-propyl}-1-methyl-1H-pyridin-2-oneHCID 57421316—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-cacb7f61a0da409c878b477b9e3d6fc5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)