(+)-1-(1-Naphthyl)ethylamine → 1-(1-Naphthyl)ethylamine

HRID 1915193Notes

Reaction equation

HRID 1915193 reaction equation
[C:1]1([C@H:11]([NH2:13])[CH3:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.FC(F)(F)C1C=C(C=CC=O)C=CC=1>>[C:1]1([CH:11]([NH2:13])[CH3:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 2724264(+)-1-(1-Naphthyl)ethylamineHCID 534010893-[3-(Trifluoromethyl)phenyl]-2-propenal

Product 1

HCID 980891-(1-Naphthyl)ethylamine

Procedure

which includes the following steps: a) reacting (R)-(+)-1-(1-naphthyl)ethylamine (II) with 3-[3-(trifluoromethyl)phenyl]propenaldehyde (III) to afford the non isolated intermediate (R)—N-[3-[3-(trifluoromethyl)phenyl]-2-propenylimino-N-[1-(1-naphthyl)ethylamine (IV)

Sources & evidence

ORD record
ord-c3947f6d7ddb45e6a1fb70aaf4e9cde4
Source dataset
uspto-grants-2013_12
Patent number
US08614354B2

Reaction notes

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