2-Chlorobenzenesulfonyl chloride → 5-[4-(2-Chlorobenzenesulfonyl)piperidin-4-ylmethoxy]quinazoline-2,4-diamine
Reaction equation
[Cl:21][c:22]1[c:23]([S:28](=[O:29])(=[O:30])[Cl:31])[cH:24][cH:25][cH:26][cH:27]1.[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:7][O:8][c:9]2[c:10]3[c:11]([NH2:20])[n:12][c:13]([NH2:19])[n:14][c:15]3[cH:16][cH:17][cH:18]2)[CH2:5][CH2:6]1>>[NH:1]1[CH2:2][CH2:3][C:4]([CH2:7][O:8][c:9]2[c:10]3[c:11]([NH2:20])[n:12][c:13]([NH2:19])[n:14][c:15]3[cH:16][cH:17][cH:18]2)([S:28]([c:23]2[c:22]([Cl:21])[cH:27][cH:26][cH:25][cH:24]2)(=[O:29])=[O:30])[CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-e3bf40ae68654a06a1d011bb2c5760cd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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