HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 5-Amino-4-fluoro-2-(1-methylcyclohexyl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | 1-Methylcyclohexanol | HCID 11550 | — |
| Product | 5-Amino-4-fluoro-2-(1-methylcyclohexyl)phenol | HCID 57470221 | — |
Reaction Steps
5-Amino-4-fluoro-2-(1-methylcyclohexyl)phenol (C-13) was synthesized following the general scheme above starting from 4-fluorophenol and 1-methylcyclohexanol. Overall yield (3%). HPLC ret. time 3.00 min, 10-99% CH3CN, 5 min run; ESI-MS 224.2 m/z (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08614327B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-f7bc44bf5e564368a1d908c15f7869c3 |
| Source note | uspto-grants-2013_12 |