HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 4-(3-Bromo-6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 4-(6-Phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde | HCID 86630655 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-(3-Bromo-6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde | HCID 86630658 | — |
Reaction Steps
1.5 g 4-(6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde (prepared as described under example 1) and 0.9 g NBS are refluxed in 30 ml chloroform for 1 h. The solvent is removed by distillation and the crude product is purified by column chromatography (dichloromethane/methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08614218B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-069b8e159c57424f8f38aa1dfc5150e2 |
| Source note | uspto-grants-2013_12 |