HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1915550Generated: October 25, 2026
4-(6-Phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde → 1-[4-(6-Phenylimidazo[1,2-a]pyrimidin-7-yl)phenyl]ethanol
https://huagongshe.com/reaction/1915550
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-(6-Phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde | HCID 86630655 | — |
| Reactant | HCID 178477798 | HCID 178477798 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-[4-(6-Phenylimidazo[1,2-a]pyrimidin-7-yl)phenyl]ethanol | HCID 68459225 | — |
Reaction Steps
100 mg 4-(6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde (prepared as described for example 1) are dissolved in 2 ml THF and 1 ml of a 2M solution of MeZnCl is added. The mixture is heated (100° C., microwave) for 2 h, cooled to room temperature and extracted with a mixture of dichloromethane and water. The organic layers are dried over sodium sulphate and the solvent is evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08614218B2 |
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| Source dataset | uspto-grants-2013_12 |
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| ORD ID | ord-e153f07964614af0ab2dfebff5fe6ecf |
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| Source note | uspto-grants-2013_12 |
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