HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 4-[2-(4-Nitrophenyl)ethyl]morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 4-Nitrophenethyl bromide | HCID 79266 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-[2-(4-Nitrophenyl)ethyl]morpholine | HCID 2797473 | — |
Reaction Steps
To 4-(2-bromoethyl)-1-nitrobenzene (1 eq) in tetrahydrofuran was added morpholine (3 eq) and stir for 16 h at ambient temperature. Concentrating and passing through a plug of silica gave 4-[2-(4-nitrophenyl)ethylmorpholine. MS: MH+=236.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08614330B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-7d6fda8c73344f24aa5dc211f7036103 |
| Source note | uspto-grants-2013_12 |