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HRID1915760

反应详情

EQUATION

反应方程式

HRID 1915760 的结构方程式

REACTANTS

反应物

2
结构：Cn1ncc([N+](=O)[O-])c1Cl
HCID12344836

5-chloro-1-methyl-4-nitro-1H-pyrazole

C4H4ClN3O2

结构：CC[C@@H]1CN(C(=O)OC(C)(C)C)CCN1
HCID24820337

tert-Butyl (3R)-3-ethylpiperazine-1-carboxylate

C11H22N2O2

PRODUCTS

生成物

1
结构：CC[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1c(N)cnn1C
HCID86679973

未命名化合物

PROCEDURE

实验过程

Following the procedure for Intermediate 10 starting from 5-chloro-1-methyl-4-nitro-1H-pyrazole from Example 1 and (R)-tert-butyl 3-ethylpiperazine-1-carboxylate gave (R)-tert-butyl 4-(4-amino-1-methyl-1H-pyrazol-5-yl)-3-ethylpiperazine-1-carboxylate as an orange gum (118 mg, 67% over two steps). LCMS (ES+) m/z 310 (M+1).