HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 191599Generated: October 31, 2026
Diethyl Ether → 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[1-(2,2,2-trifluoroethyl)piperidin-4-ylmethoxy]quinazoline
https://huagongshe.com/reaction/191599
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 2,2,2-Trifluoroethyl trifluoromethanesulfonate | HCID 80366 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(piperidin-4-ylmethoxy)quinazoline | HCID 58960220 | — |
| Product | 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[1-(2,2,2-trifluoroethyl)piperidin-4-ylmethoxy]quinazoline | HCID 10289370 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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| ORD ID | ord-20b233c43ce94ca89f427740f22c6529 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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