Tacrolimus → HCID 87059324, compound

Participants

Reaction Steps

FK506, which is not water soluble, was mixed with Matrigel™ (as a suspension) at 10 μg/μl, and 1.2 μl were injected into the subretinal space as described above. Eyes were collected 10 days after injection and blood vessels were stained with Vessel Paint. Eyes were embedded in 5% agarose and serial sections were cut (100 μm thick) on a vibratome. CNV was examined by fluorescence microscopy and CNV index of each eye was calculated. Results are shown below.

Provenance & Evidence