Potassium Cation → 2-[2-(4-Benzhydrylsulfanyl-piperidin-1-yl)-ethyl]-isoindole-1,3-dione

HRID 191611Notes

Reaction equation

HRID 191611 reaction equation
[Br:21][CH2:22][CH2:23][N:24]1[C:25](=[O:34])[c:26]2[c:27]([cH:30][cH:31][cH:32][cH:33]2)[C:28]1=[O:29].[CH3:43][C:44](=[O:45])[CH2:46][CH3:47].[CH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[S:14][CH:15]1[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]1.[I-:41].[K+:35].[K+:36].[Na+:42].[O-:37][C:38]([O-:39])=[O:40]>>[CH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[S:14][CH:15]1[CH2:16][CH2:17][N:18]([CH2:22][CH2:23][N:24]2[C:25](=[O:34])[c:26]3[c:27]([cH:30][cH:31][cH:32][cH:33]3)[C:28]2=[O:29])[CH2:19][CH2:20]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 923Sodium ionHCID 6569Methyl Ethyl KetoneHCID 113251H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)-HCID 19660Carbonate IonHCID 30165Iodide IonHCID 10469071HCID 10469071, compound

Product 1

HCID 211877862-[2-(4-Benzhydrylsulfanyl-piperidin-1-yl)-ethyl]-isoindole-1,3-dione

Sources & evidence

ORD record
ord-d8bce0a9b9c54c978528620d678f55c5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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