HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethylpyridin-2-amine → 4-Ethyl-5-iodopyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethylpyridin-2-amine | HCID 118425 | — |
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Product | 4-Ethyl-5-iodopyridin-2-amine | HCID 58200578 | — |
Reaction Steps
The title compound is synthesized according to general procedure GP1 starting from 5.0 g (41 mmol) 4-ethyl-pyridin-2-ylamine and 9.2 g (41 mmol) NIS. Yield after precipitation from the reaction mixture and isolation of additional product from the mother liquid by chromatography using silica gel: 10.3 g (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618111B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-d9881e1b0d4a4f8396760f02c97c9583 |
| Source note | uspto-grants-2013_12 |