HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 178510541, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Benzaldehyde, 4-(2-hydroxyethoxy)- | HCID 89178 | — |
| Reactant | 4-Amino-1,2-dihydropyridin-2-one | HCID 573530 | — |
| Reactant | 2-Cyanoethanethioamide | HCID 1416277 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 178510541 | HCID 178510541 | — |
Reaction Steps
1 g (9.08 mmol) of 4-aminopyridin-2(1H)-one [Searls, T., McLaughlin, L. W., Tetrahedron 55, 11985-11996 (1999)], 1.509 g (9.08 mmol) of 4-(2-hydroxyethoxy)benzaldehyde and 0.909 g (9.08 mmol) of 2-cyanoethanethioamide were initially charged in 50 ml of 2-propanol, 0.78 ml (13.62 mmol) of acetic acid was added and the mixture was stirred at reflux overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618119B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-7cf86c2760e144bf9a4dbdc516b33fdd |
| Source note | uspto-grants-2013_12 |