HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916265Generated: November 1, 2026
Sodium Sulfide → Sodium [3-cyano-4-phenyl-6,7-dihydro-5H-cyclopenta[b]pyridine-2-thiolate]
https://huagongshe.com/reaction/1916265
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Sulfide | HCID 14804 | — |
| Reactant | 2-chloro-4-phenyl-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile | HCID 58158135 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Sodium [3-cyano-4-phenyl-6,7-dihydro-5H-cyclopenta[b]pyridine-2-thiolate] | HCID 66932949 | — |
Reaction Steps
147 mg (1.89 mmol) of sodium sulfide are added to a solution of 400 mg (1.57 mmol) of the compound from Example 17A in 4.8 ml DMF, and the mixture was stirred at 30° C. for 5 h. Without further work-up, the reaction mixture was directly reacted further.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08618119B2 |
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| Source dataset | uspto-grants-2013_12 |
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| ORD ID | ord-450d071658da436994ae407f508b83b1 |
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| Source note | uspto-grants-2013_12 |
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