p-Toluenesulfonic acid monohydrate → HCID 58158152, compound

Participants

Reaction Steps

50 mg (0.093 mmol) of the compound from Example 22A were initially charged in 2 ml of acetone, a spatula tip of 4-toluenesulfonic acid monohydrate was added and the mixture was stirred at reflux for 1 h. After cooling, the reaction solution was concentrated and the residue was purified directly by preparative HPLC (Chromasil, water/acetonitrile+0.1% TFA).

Provenance & Evidence