HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → HCID 86656445, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 86241604 | HCID 86241604 | — |
| Solvent | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Product | HCID 86656445 | HCID 86656445 | 44% |
Reaction Steps
A solution of 2-methoxy-8-(2-oxiranyl)-quinoline (900 mg; prepared according to WO 2006/046552) in dioxane/water (5:1; 60 mL) was reacted with NaN3 at 90° C. for 5 h. The solvents were removed under reduced pressure and the residue was purified by CC (Hex/EA 2:1 to 1:1), affording a yellow oil (480 mg; 44% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618092B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-f7c5a35be9fa4ff48245e8383003a648 |
| Source note | uspto-grants-2013_12 |