Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → HCID 67066687, compound

Participants

Reaction Steps

A solution of 2-methoxy-4-nitrobenzaldehyde (904 mg, 4.99 mmol) and methyl (triphenylphosphoranylidene) acetate (2.04 g, 5.86 mmol) in CH2Cl2 (25.0 mL) was stirred at 20° C. for 14 h. The solvent was evaporated under reduced pressure and the residue was chromatographed (SiO2 230-400 mesh, 4/1 hexanes/EtOAc) to give the title compound (1.18 g, 4/1 E/Z isomeric mixture, quant.) as a white solid. MS (electrospray, +ions) m/z 238 (M+H).

Provenance & Evidence