(2,5-Dichloro-pyrimidin-4-yl)-(2-pyrazol-1-yl-phenyl)-amine → 5-Chloro-N(2)-(1,4-diethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl)-N(4)-(2-pyrazol-1-yl-phenyl)-pyrimidine-2,4-diamine

HRID 191653Notes

Reaction equation

HRID 191653 reaction equation
[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([CH2:15][CH3:16])[CH2:7][c:8]2[c:9]1[cH:10][c:11]([NH2:14])[cH:12][cH:13]2.[Cl:17][c:18]1[n:19][cH:20][c:21]([Cl:36])[c:22]([NH:24][c:25]2[c:26](-[n:31]3[n:32][cH:33][cH:34][cH:35]3)[cH:27][cH:28][cH:29][cH:30]2)[n:23]1>>[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([CH2:15][CH3:16])[CH2:7][c:8]2[c:9]1[cH:10][c:11]([NH:14][c:18]1[n:19][cH:20][c:21]([Cl:36])[c:22]([NH:24][c:25]3[c:26](-[n:31]4[n:32][cH:33][cH:34][cH:35]4)[cH:27][cH:28][cH:29][cH:30]3)[n:23]1)[cH:12][cH:13]2

Participants

3

Reactant 2

HCID 57853883(2,5-Dichloro-pyrimidin-4-yl)-(2-pyrazol-1-yl-phenyl)-amineHCID 672642811,4-Diethyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-8-ylamine

Product 1

HCID 672649165-Chloro-N(2)-(1,4-diethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl)-N(4)-(2-pyrazol-1-yl-phenyl)-pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-589863e9ebed47e194ff35fe489bfb19
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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