5-Bromo-2-(2-(pyrrolidin-1-yl)ethoxy)pyridine → HCID 10024145, compound

HRID 1916568Notes

Reaction equation

HRID 1916568 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([O:8][CH2:9][CH2:10][N:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[N:6][CH:7]=1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([C:23]2[CH:24]=[CH:25][C:26]([C:29]#[CH:30])=[N:27][CH:28]=2)=[CH:19][CH:18]=1>>[Cl:16][C:17]1[CH:18]=[CH:19][C:20]([C:23]2[CH:24]=[CH:25][C:26]([C:29]#[C:30][C:2]3[CH:3]=[CH:4][C:5]([O:8][CH2:9][CH2:10][N:11]4[CH2:15][CH2:14][CH2:13][CH2:12]4)=[N:6][CH:7]=3)=[N:27][CH:28]=2)=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 105881665-Bromo-2-(2-(pyrrolidin-1-yl)ethoxy)pyridineHCID 578453285-(4-Chloro-phenyl)-2-ethynyl-pyridine

Product 1

HCID 10024145HCID 10024145, compound

Procedure

Prepared according to general working method I from 5-bromo-2-(2-pyrrolidin-1-yl-ethoxy)-pyridine (90 mg, 0.33 mmol) and 5-(4-chloro-phenyl)-2-ethynyl-pyridine (80 mg, 0.37 mmol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6bb830c8d5744bc58eefbfb3cb6ed8b4
Source dataset
uspto-grants-2013_12
Patent number
US08618132B2

Reaction notes

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