5-(4-Chloro-phenyl)-2-ethynyl-pyridine → HCID 10048194, compound

HRID 1916611Notes

Reaction equation

HRID 1916611 reaction equation
I[C:2]1[CH:3]=[C:4]2[N:10]=[CH:9][N:8]([CH2:11][CH2:12][N:13]3[CH2:17][CH2:16][CH2:15][CH2:14]3)[C:5]2=[N:6][CH:7]=1.[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]2[CH:26]=[CH:27][C:28]([C:31]#[CH:32])=[N:29][CH:30]=2)=[CH:21][CH:20]=1>>[Cl:18][C:19]1[CH:20]=[CH:21][C:22]([C:25]2[CH:26]=[CH:27][C:28]([C:31]#[C:32][C:2]3[CH:3]=[C:4]4[N:10]=[CH:9][N:8]([CH2:11][CH2:12][N:13]5[CH2:17][CH2:16][CH2:15][CH2:14]5)[C:5]4=[N:6][CH:7]=3)=[N:29][CH:30]=2)=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 578453285-(4-Chloro-phenyl)-2-ethynyl-pyridineHCID 69074163HCID 69074163, compound

Product 1

HCID 10048194HCID 10048194, compound

Procedure

Prepared according to general working method I from 6-iodo-3-(2-pyrrolidin-1-yl-ethyl)-3H-imidazo[4,5-b]pyridine (300 mg, 0.88 mmol) and 5-(4-chloro-phenyl)-2-ethynyl-pyridine (187 mg, 0.88 mmol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f1c62dac5633428aa45f5362ec9c9aae
Source dataset
uspto-grants-2013_12
Patent number
US08618132B2

Reaction notes

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