HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Chloro-phenyl)-2-ethynyl-pyridine → 5-(4-Chloro-phenyl)-2-[4-(1-methyl-2-piperidin-1-yl-ethoxy)-phenylethynyl]-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Chloro-phenyl)-2-ethynyl-pyridine | HCID 57845328 | — |
| Reactant | 1-[2-(4-Iodo-phenoxy)-propyl]-piperidine | HCID 69074101 | — |
| Product | 5-(4-Chloro-phenyl)-2-[4-(1-methyl-2-piperidin-1-yl-ethoxy)-phenylethynyl]-pyridine | HCID 10048363 | — |
Reaction Steps
Prepared according to general working method I from 1-[2-(4-iodo-phenoxy)-propyl]-piperidine (173 mg, 0.50 mmol) and 5-(4-chloro-phenyl)-2-ethynyl-pyridine (107 mg, 0.50 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618132B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-b8f4291cb56646148372cf886245aec0 |
| Source note | uspto-grants-2013_12 |