5-(4-Chloro-phenyl)-2-ethynyl-pyridine → HCID 67363469, compound

HRID 1916647Notes

Reaction equation

HRID 1916647 reaction equation
I[C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([CH2:10][OH:11])=[CH:7][C:6]=2[CH:12]=1.[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([C:20]2[CH:21]=[CH:22][C:23]([C:26]#[CH:27])=[N:24][CH:25]=2)=[CH:16][CH:15]=1>>[Cl:13][C:14]1[CH:15]=[CH:16][C:17]([C:20]2[CH:21]=[CH:22][C:23]([C:26]#[C:27][C:2]3[CH:3]=[CH:4][C:5]4[O:9][C:8]([CH2:10][OH:11])=[CH:7][C:6]=4[CH:12]=3)=[N:24][CH:25]=2)=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 578453285-(4-Chloro-phenyl)-2-ethynyl-pyridineHCID 69077593HCID 69077593, compound

Product 1

HCID 67363469HCID 67363469, compound

Procedure

Prepared according to general working method I from (5-iodo-benzofuran-2-yl)-methanol (685 mg, 2.50 mmol) and 5-(4-chloro-phenyl)-2-ethynyl-pyridine (534 mg, 2.50 mmol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1a3a1b5ac97543058d5a46262829cbe9
Source dataset
uspto-grants-2013_12
Patent number
US08618132B2

Reaction notes

Loading…