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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916680Generated: October 30, 2026

5-Bromo-2-ethynylpyridine → 5-Bromo-2-{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenylethynyl}pyridine

https://huagongshe.com/reaction/1916680

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-ethynylpyridineHCID 13979734—
Reactant1-(2-(4-Iodophenoxy)ethyl)-4-methylpiperidineHCID 69061017—
Product5-Bromo-2-{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenylethynyl}pyridineHCID 69060172—

Reaction Steps

Prepared according to general working method I from 1-[2-(4-iodo-phenoxy)-ethyl]-4-methyl-piperidine (345 mg, 1.00 mmol) and 5-bromo-2-ethynyl-pyridine (83 mg, 0.39 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-069bb95d5ce44f66b402b5a52ed9a281
Source noteuspto-grants-2013_12