Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916759Generated: November 1, 2026

1-[2-(3-Ethynyl-phenoxy)-ethyl]-pyrrolidine → 6-(4-Chloro-phenyl)-2-[3-(2-pyrrolidin-1-yl-ethoxy)-phenylethynyl]-quinoline

https://huagongshe.com/reaction/1916759

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-(3-Ethynyl-phenoxy)-ethyl]-pyrrolidineHCID 85969558—
Reactant2-Bromo-6-(4-chloro-phenyl)-quinolineHCID 85969692—
Product6-(4-Chloro-phenyl)-2-[3-(2-pyrrolidin-1-yl-ethoxy)-phenylethynyl]-quinolineHCID 59835884—

Reaction Steps

Prepared analogously to Example 18d from 1-[2-(3-ethynyl-phenoxy)-ethyl]-pyrrolidine and 2-bromo-6-(4-chloro-phenyl)-quinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-3e540a923caf44f78c3adf4863953a6a
Source noteuspto-grants-2013_12