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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916763Generated: November 2, 2026

Trimethylsilylacetylene → 2-Pyrrolidin-1-ylmethyl-5-trimethylsilanylethynyl-benzoxazole

https://huagongshe.com/reaction/1916763

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant5-Iodo-2-pyrrolidin-1-ylmethyl-benzoxazoleHCID 69072380—
Product2-Pyrrolidin-1-ylmethyl-5-trimethylsilanylethynyl-benzoxazoleHCID 67363514—

Reaction Steps

Prepared analogously to Example 18b from 5-iodo-2-pyrrolidin-1-ylmethyl-benzoxazole and ethynyl-trimethyl-silane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-2156166ebf684349a4a09b4fefef3108
Source noteuspto-grants-2013_12