6-chloroimidazo[1,2-a]pyridine-2-carboxylic acid → HCID 25271462, compound

HRID 1916921Notes

Reaction equation

HRID 1916921 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[Cl:20][C:21]1[CH:22]=[CH:23][C:24]2[N:25]([CH:27]=[C:28]([C:30](O)=[O:31])[N:29]=2)[CH:26]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:30]([C:28]1[N:29]=[C:24]2[CH:23]=[CH:22][C:21]([Cl:20])=[CH:26][N:25]2[CH:27]=1)=[O:31]

Participants

3

Reactant 2

HCID 27576146-chloroimidazo[1,2-a]pyridine-2-carboxylic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

Product 1

HCID 25271462HCID 25271462, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 6-Chloro-imidazo[1,2-a]pyridine-2-carboxylic acid. MS: 438.4 (M+H).

Sources & evidence

ORD record
ord-3a6a9836f9d54949bf2f1138b59f5a8c
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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