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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916922Generated: October 26, 2026

4-Oxo-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid → 4-Oxo-4,5,6,7-tetrahydro-benzofuran-2-carboxylic acid [2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amide

https://huagongshe.com/reaction/1916922

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Oxo-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acidHCID 3471008—
Reactant2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamineHCID 59401830—
Product4-Oxo-4,5,6,7-tetrahydro-benzofuran-2-carboxylic acid [2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amideHCID 67401881—

Reaction Steps

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-oxo-4,5,6,7-tetrahydro-benzofuran-2-carboxylic acid. MS: 422.4 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618159B2
Source datasetuspto-grants-2013_12
ORD IDord-5bb73138eecf442ca922625f7d511d39
Source noteuspto-grants-2013_12