2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine → HCID 178428010, compound

HRID 1916927Notes

Reaction equation

HRID 1916927 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[N:20]1[CH:25]=[CH:24][CH:23]=[C:22]([C:26]2[NH:30][C:29]3[CH:31]=[CH:32][C:33]([C:35](O)=[O:36])=[CH:34][C:28]=3[N:27]=2)[CH:21]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:35]([C:33]1[CH:32]=[CH:31][C:29]2[NH:30][C:26]([C:22]3[CH:21]=[N:20][CH:25]=[CH:24][CH:23]=3)=[N:27][C:28]=2[CH:34]=1)=[O:36]

Participants

3

Reactant 2

HCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamineHCID 178524158HCID 178524158, compound

Product 1

HCID 178428010HCID 178428010, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 2-pyridin-3-yl-1H-benzoimidazole-5-carboxylic acid. MS: 481.3 (M+H).

Sources & evidence

ORD record
ord-9c144d09fd124ef38d1d96f7ef353f1f
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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