4H-1-Benzopyran-2-carboxylic acid, 6-chloro-4-oxo- → HCID 59401844, compound

HRID 1916928Notes

Reaction equation

HRID 1916928 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[Cl:20][C:21]1[CH:22]=[C:23]2[C:28](=[CH:29][CH:30]=1)[O:27][C:26]([C:31](O)=[O:32])=[CH:25][C:24]2=[O:34]>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:31]([C:26]1[O:27][C:28]2[C:23]([C:24](=[O:34])[CH:25]=1)=[CH:22][C:21]([Cl:20])=[CH:30][CH:29]=2)=[O:32]

Participants

3

Reactant 2

HCID 211074H-1-Benzopyran-2-carboxylic acid, 6-chloro-4-oxo-HCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

Product 1

HCID 59401844HCID 59401844, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 6-chloro-4-oxo-4H-chromene-2-carboxylic acid. MS: 466.2 (M+H).

Sources & evidence

ORD record
ord-664cbf756232470899e371c33fad7aae
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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