2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine → HCID 59401849, compound

HRID 1916929Notes

Reaction equation

HRID 1916929 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[Cl:20][C:21]1[C:22]([NH:30][CH2:31][CH2:32][OH:33])=[N:23][CH:24]=[C:25]([CH:29]=1)[C:26](O)=[O:27]>>[Cl:20][C:21]1[C:22]([NH:30][CH2:31][CH2:32][OH:33])=[N:23][CH:24]=[C:25]([CH:29]=1)[C:26]([NH:19][C:3]1[CH:4]=[CH:5][C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)=[CH:7][C:2]=1[CH3:1])=[O:27]

Participants

3

Reactant 2

HCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamineHCID 62489723HCID 62489723, compound

Product 1

HCID 59401849HCID 59401849, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 5-chloro-6-(2-hydroxy-ethylamino)-nicotinic acid. MS: 458.4 (M+H).

Sources & evidence

ORD record
ord-4fab00ddf3384907a50de1ae89f65173
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

Loading…