5-Methoxybenzofuran-2-carboxylic acid → 5-Methoxy-benzofuran-2-carboxylic acid [2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amide
Reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[CH3:20][O:21][C:22]1[CH:23]=[CH:24][C:25]2[O:29][C:28]([C:30](O)=[O:31])=[CH:27][C:26]=2[CH:33]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:30]([C:28]1[O:29][C:25]2[CH:24]=[CH:23][C:22]([O:21][CH3:20])=[CH:33][C:26]=2[CH:27]=1)=[O:31]Participants
3
Procedure
The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 5-methoxy-benzofuran-2-carboxylic acid. MS: 434.2 (M+H).
Sources & evidence
- ORD record
- ord-8eb0e4a9877442188a28624fd4df9f7f
- Source dataset
- uspto-grants-2013_12
- Patent number
- US08618159B2
Reaction notes
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