2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine → HCID 178422959, compound

HRID 1916933Notes

Reaction equation

HRID 1916933 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[OH:20][C:21]1[C:30]2[C:25](=[N:26][C:27]([CH3:31])=[CH:28][CH:29]=2)[N:24]=[CH:23][C:22]=1[C:32](O)=[O:33]>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:32]([C:22]1[CH:23]=[N:24][C:25]2[C:30]([C:21]=1[OH:20])=[CH:29][CH:28]=[C:27]([CH3:31])[N:26]=2)=[O:33]

Participants

3

Reactant 2

HCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamineHCID 178422970HCID 178422970, compound

Product 1

HCID 178422959HCID 178422959, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-hydroxy-7-methyl-[1,8]naphthyridine-3-carboxylic acid. MS: 446.5 (M+H).

Sources & evidence

ORD record
ord-12524b5a37c347d289f6ab9c1ece7cd6
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

Loading…