2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine → HCID 178428009, compound
Reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[C:26]1[NH:30][C:29]2[CH:31]=[CH:32][C:33]([C:35](O)=[O:36])=[CH:34][C:28]=2[N:27]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:35]([C:33]1[CH:32]=[CH:31][C:29]2[NH:30][C:26]([C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][N:20]=3)=[N:27][C:28]=2[CH:34]=1)=[O:36]Participants
3
Procedure
The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 2-pyridin-2-yl-1H-benzoimidazole-5-carboxylic acid. MS: 481.3 (M+H).
Sources & evidence
- ORD record
- ord-3450971286ea45daa8f4b27257357c3e
- Source dataset
- uspto-grants-2013_12
- Patent number
- US08618159B2
Reaction notes
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