2,4-Dimethylbenzoyl chloride → HCID 59401817, compound

HRID 1916939Notes

Reaction equation

HRID 1916939 reaction equation
[CH3:1][CH:2]1[CH2:6][CH2:5][CH2:4][N:3]1[CH:7]1[CH2:11][CH2:10][N:9]([C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[C:14]([C:19]([F:22])([F:21])[F:20])[CH:13]=2)[CH2:8]1.[CH3:23][C:24]1[CH:32]=[C:31]([CH3:33])[CH:30]=[CH:29][C:25]=1[C:26](Cl)=[O:27]>>[CH3:23][C:24]1[CH:32]=[C:31]([CH3:33])[CH:30]=[CH:29][C:25]=1[C:26]([NH:18][C:15]1[CH:16]=[CH:17][C:12]([N:9]2[CH2:10][CH2:11][CH:7]([N:3]3[CH2:4][CH2:5][CH2:6][CH:2]3[CH3:1])[CH2:8]2)=[CH:13][C:14]=1[C:19]([F:22])([F:20])[F:21])=[O:27]

Participants

3

Reactant 2

HCID 1408672,4-Dimethylbenzoyl chlorideHCID 66625311HCID 66625311, compound

Product 1

HCID 59401817HCID 59401817, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-2-trifluoromethyl-phenylamine with 2,4-dimethyl benzoyl chloride. MS: 446.2 (M+H).

Sources & evidence

ORD record
ord-1f3615eb7610475092d5dae3742023fd
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

Loading…