2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine → HCID 25266594, compound

HRID 1916940Notes

Reaction equation

HRID 1916940 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[CH3:20][C:21]1[C:25]([C:26]2[CH:34]=[CH:33][C:29]([C:30](O)=[O:31])=[CH:28][CH:27]=2)=[C:24]([CH3:35])[NH:23][N:22]=1>>[CH3:35][C:24]1[C:25]([C:26]2[CH:34]=[CH:33][C:29]([C:30]([NH:19][C:3]3[CH:4]=[CH:5][C:6]([N:8]4[CH2:12][CH2:11][CH:10]([N:13]5[CH2:17][CH2:16][CH2:15][CH:14]5[CH3:18])[CH2:9]4)=[CH:7][C:2]=3[CH3:1])=[O:31])=[CH:28][CH:27]=2)=[C:21]([CH3:20])[NH:22][N:23]=1

Participants

3

Reactant 2

HCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamineHCID 674005104-(3,5-Dimethyl-1H-pyrazol-4-yl)benzoic acid

Product 1

HCID 25266594HCID 25266594, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-(3,5-dimethyl-1H-pyrazol-4-yl)benzoic acid. MS: 458.3 (M+H).

Sources & evidence

ORD record
ord-5966b2e17985443d9ca885b5d242fe2c
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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