4-(2-Oxopyrrolidin-1-yl)benzoic acid → HCID 59401761, compound

HRID 1916941Notes

Reaction equation

HRID 1916941 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[O:20]=[C:21]1[CH2:25][CH2:24][CH2:23][N:22]1[C:26]1[CH:34]=[CH:33][C:29]([C:30](O)=[O:31])=[CH:28][CH:27]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:30](=[O:31])[C:29]1[CH:28]=[CH:27][C:26]([N:22]2[CH2:23][CH2:24][CH2:25][C:21]2=[O:20])=[CH:34][CH:33]=1

Participants

3

Reactant 2

HCID 7731304-(2-Oxopyrrolidin-1-yl)benzoic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

Product 1

HCID 59401761HCID 59401761, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-(2-oxo-pyrrolidin-1-yl)-benzoic acid. MS: 447.5 (M+H).

Sources & evidence

ORD record
ord-4ac2539d6b7048129701b2e7d21c9eea
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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