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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916945Generated: October 26, 2026

1,4-Benzodioxane-6-carboxylic Acid → 2,3-Dihydro-benzo[1,4]dioxine-6-carboxylic acid[2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amide

https://huagongshe.com/reaction/1916945

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Benzodioxane-6-carboxylic AcidHCID 2758833—
Reactant2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamineHCID 59401830—
Product2,3-Dihydro-benzo[1,4]dioxine-6-carboxylic acid[2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amideHCID 59401868—

Reaction Steps

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 2,3-dihydro-benzo[1,4]dioxine-6-carboxylic acid. MS: 422.4 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618159B2
Source datasetuspto-grants-2013_12
ORD IDord-368ed84b933a4e6cb38a8a09da08449d
Source noteuspto-grants-2013_12