2-(3-Pyridyl)thiazole-4-carboxylic acid → HCID 25266930, compound

HRID 1916946Notes

Reaction equation

HRID 1916946 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[N:20]1[CH:25]=[CH:24][CH:23]=[C:22]([C:26]2[S:27][CH:28]=[C:29]([C:31](O)=[O:32])[N:30]=2)[CH:21]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:31]([C:29]1[N:30]=[C:26]([C:22]2[CH:21]=[N:20][CH:25]=[CH:24][CH:23]=2)[S:27][CH:28]=1)=[O:32]

Participants

3

Reactant 2

HCID 7365132-(3-Pyridyl)thiazole-4-carboxylic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

Product 1

HCID 25266930HCID 25266930, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 2-pyridin-3-yl-thiazole-4-carboxylic acid. MS: 448.2 (M+H).

Sources & evidence

ORD record
ord-fc12dfac397c47b7b4927803b7621d1a
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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