1,6-Naphthyridine-2-carboxylic acid → HCID 59401832, compound

HRID 1916949Notes

Reaction equation

HRID 1916949 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[N:20]1[C:29]2[C:24](=[CH:25][N:26]=[CH:27][CH:28]=2)[CH:23]=[CH:22][C:21]=1[C:30](O)=[O:31]>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:30]([C:21]1[CH:22]=[CH:23][C:24]2[C:29](=[CH:28][CH:27]=[N:26][CH:25]=2)[N:20]=1)=[O:31]

Participants

3

Reactant 2

HCID 7359081,6-Naphthyridine-2-carboxylic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

Product 1

HCID 59401832HCID 59401832, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with [1,6]naphthyridine-2-carboxylic acid. MS: 416.4 (M+H).

Sources & evidence

ORD record
ord-9391dcac7e3b4241a31096fe0efaa12d
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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