2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine → HCID 59401847, compound
Reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[CH3:20][S:21]([C:24]1[CH:25]=[C:26]([CH:30]=[CH:31][C:32]=1[CH3:33])[C:27](Cl)=[O:28])(=[O:23])=[O:22]>>[CH3:20][S:21]([C:24]1[CH:25]=[C:26]([CH:30]=[CH:31][C:32]=1[CH3:33])[C:27]([NH:19][C:3]1[CH:4]=[CH:5][C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)=[CH:7][C:2]=1[CH3:1])=[O:28])(=[O:22])=[O:23]Participants
3
Procedure
The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 3-methane-sulfonyl-4-methyl-benzoyl chloride. MS: 456.2 (M+H).
Sources & evidence
- ORD record
- ord-5a0c3b12d8f542df8ad92f568271decf
- Source dataset
- uspto-grants-2013_12
- Patent number
- US08618159B2
Reaction notes
Loading…