4-benzoyl-1H-pyrrole-2-carboxylic Acid → HCID 25266933, compound

HRID 1916954Notes

Reaction equation

HRID 1916954 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[C:20]([C:28]1[CH:29]=[C:30]([C:33](O)=[O:34])[NH:31][CH:32]=1)(=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:33]([C:30]1[NH:31][CH:32]=[C:28]([C:20](=[O:27])[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:29]=1)=[O:34]

Participants

3

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-benzoyl-1H-pyrrole-2-carboxylic acid. MS: 457.4 (M+H).

Sources & evidence

ORD record
ord-7e23ec101d3544458af807276dc98b24
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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