5-Methoxyindole-2-carboxylic acid → HCID 59401811, compound

HRID 1916964Notes

Reaction equation

HRID 1916964 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[CH3:20][O:21][C:22]1[CH:23]=[C:24]2[C:28](=[CH:29][CH:30]=1)[NH:27][C:26]([C:31](O)=[O:32])=[CH:25]2>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:31]([C:26]1[NH:27][C:28]2[C:24]([CH:25]=1)=[CH:23][C:22]([O:21][CH3:20])=[CH:30][CH:29]=2)=[O:32]

Participants

3

Reactant 2

HCID 204015-Methoxyindole-2-carboxylic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

Product 1

HCID 59401811HCID 59401811, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 5-methoxy-1H-indole-2-carboxylic acid. MS: 433.2 (M+H).

Sources & evidence

ORD record
ord-0113cb7561214a85983b0ff649ea4568
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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