6-(1H-pyrazol-1-yl)nicotinic acid → HCID 59401772, compound

HRID 1916965Notes

Reaction equation

HRID 1916965 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[N:20]1([C:25]2[CH:33]=[CH:32][C:28]([C:29](O)=[O:30])=[CH:27][N:26]=2)[CH:24]=[CH:23][CH:22]=[N:21]1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:29](=[O:30])[C:28]1[CH:32]=[CH:33][C:25]([N:20]2[CH:24]=[CH:23][CH:22]=[N:21]2)=[N:26][CH:27]=1

Participants

3

Reactant 2

HCID 27636146-(1H-pyrazol-1-yl)nicotinic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

Product 1

HCID 59401772HCID 59401772, compound

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 6-pyrazol-1-yl-nicotinic acid. MS: 431.4 (M+H).

Sources & evidence

ORD record
ord-99070ff497224fb18ce197786a4966a4
Source dataset
uspto-grants-2013_12
Patent number
US08618159B2

Reaction notes

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